Pages

Wednesday, November 19, 2025

Human biology is ill-adapted to modern cities

A new study has found that modern cities are having a huge impact on our health and wellbeing.
Photo Credit: Patrick Robert Doyle

Researchers from Loughborough University and the University of Zurich found that rapid industrialization has reshaped human habitats so dramatically that our biology may no longer be able to keep up. 

The paper, published in Biological Reviews, highlights that densely populated, polluted, and industrialized environments are impairing core biological functions essential for survival and reproduction (i.e., the ‘evolutionary fitness’ of our species). 

These include

  • Reproductive function, including infertility and sperm decline 
  • Immune function issues, such as allergies and autoimmune disease 
  • Cognitive function problems, including slower development and faster decline 
  • Physical function decline, such as reduced strength and endurance

The authors argue that humans may now be living in environments we are not well adapted to and that this mismatch may be undermining our long-term evolutionary fitness. 

With global fertility declining and rising chronic disease, and 68 per cent of the world’s population projected to live in cities by 2050, the team behind the research states that the implications are potentially enormous. 

Dr Danny Longman, Senior Lecturer in Human Evolutionary Physiology at Loughborough University, explained: 

“For most of our evolutionary history, our biology was shaped by natural environments. In just a few generations, industrialization has rapidly reshaped the world around us - faster than evolution can keep up. 

“The Environmental Mismatch Hypothesis suggests that the very environments we have created to support modern life may now be compromising our ability to thrive and even to reproduce.” 

Dr Colin Shaw from the University of Zurich added: 

“Our findings highlight that exposure to natural environments is not a luxury - it’s a biological necessity. The more we separate ourselves from nature, the more we risk undermining the fundamental systems that keep us healthy, resilient and capable of long-term survival.” 

Research MaterialThe Human Evolutionary EcoPhysiology Research Group

Published in journal: Biological Reviews

TitleHomo sapiens, industrialization and the environmental mismatch hypothesis

Authors: Daniel P. Longman, Colin N. Shaw

Source/CreditLoughborough University

Reference Number: eco111925_01

Privacy Policy | Terms of Service | Contact Us