Ural Scientists Developed a Drug to Combat Post-Covidal Complications

According to the scientists, the university and the Ural Branch of the Russian Academy of Sciences are developing world-class materials.
Photo credit: TASS-Ural Press Center, Vladislav Burnashev

Scientists from the Ural Federal University and the Postovsky Institute of Organic Synthesis have developed a drug to combat post-covidal complications, namely, the formation of blood clots. The drug blocks the release of clot-forming compounds caused by coronavirus infection. As the scientists point out, this is a world-class achievement, as new classes of compounds capable of combating the effects of coronavirus have been discovered. Representatives of the Ural Branch of the Russian Academy of Sciences talked about this, as well as about other developments aimed at ensuring the scientific and technological sovereignty of Russia, at a press conference at TASS.

"We develop unique things. This is important to note, because now the concept of import substitution is pushed to the background, and we are talking about the scientific and technological sovereignty of the country. The fact is that import substitution implies reproduction, copying of foreign technologies. We are catching up beforehand. Scientific and technological sovereignty implies independence from external conditions and supremacy in the development of industrial samples and new materials which are superior to foreign analogues in their characteristics. Therefore, it is certain that the Ural scientists successfully solve the task of ensuring scientific and technological progress," emphasizes Victor Rudenko, Academician and Chairman of the Ural Branch of the Russian Academy of Sciences.

Too much motivation affects our decision-making

Sami El-Boustani, Assistant Professor in the Department of Basic Neurosciences at the Faculty of Medicine of the UNIGE
Credit: Sami El-Boustani

In a good or a bad mood, focused or distracted, in dire or no need: our internal states directly influence our perceptions and decision- making. While the role of motivation on the performance of behavioral tasks has been known for more than a century - thanks to the work of psychologists Robert Yerkes and John Dilligham Dodson - its precise effect on the brain remains unclear. A team from the University of Geneva (UNIGE), in collaboration with the EPFL, has revealed how motivation alters the neural circuits responsible for sensory perception preceding decision-making in mice. This study reveals why a level of motivation that is too high or too low can affect our perception and therefore our choices. These results, featured in the journal Neuron, open up new perspectives in learning methods. 

Going to work early in the morning, choosing a restaurant at lunchtime: many of our decisions are motivated by needs, such as earning a living or satisfying our hunger. However, decision-making is a complex process, which can also be influenced by external factors, such as the environment or other individuals, and by our internal states, such as our mood, our level of attention or our degree of motivation. 

Heaviest element yet detected in an exoplanet atmosphere

This artist’s impression shows an ultra-hot exoplanet, a planet beyond our Solar System, as it is about to transit in front of its host star. When the light from the star passes through the planet’s atmosphere, it is filtered by the chemical elements and molecules in the gaseous layer. With sensitive instruments, the signatures of those elements and molecules can be observed from Earth. Using the ESPRESSO instrument of ESO’s Very Large Telescope, astronomers have found the heaviest element yet in an exoplanet's atmosphere, barium, in the two ultra-hot Jupiters WASP-76 b and WASP-121 b. 
Credit: ESO/M. Kornmesser

Using the European Southern Observatory’s Very Large Telescope (ESO’s VLT), astronomers have discovered the heaviest element ever found in an exoplanet atmosphere — barium. They were surprised to discover barium at high altitudes in the atmospheres of the ultra-hot gas giants WASP-76 b and WASP-121 b — two exoplanets, planets which orbit stars outside our Solar System. This unexpected discovery raises questions about what these exotic atmospheres may be like.

“The puzzling and counterintuitive part is: why is there such a heavy element in the upper layers of the atmosphere of these planets?” says Tomás Azevedo Silva, a PhD student at the University of Porto and the Instituto de Astrofísica e Ciências do Espaço (IA) in Portugal who led the study published today in Astronomy & Astrophysics.

WASP-76 b and WASP-121 b are not ordinary exoplanets. Both are known as ultra-hot Jupiters as they are comparable in size to Jupiter whilst having extremely high surface temperatures soaring above 1000°C. This is due to their close proximity to their host stars, which also means an orbit around each star takes only one to two days. This gives these planets rather exotic features; in WASP-76 b, for example, astronomers suspect it rains iron.

Sustainable kerosene: accelerate production on an industrial scale

In the international project CARE-O-SENE, researchers are developing tailor-made Fischer-Tropsch catalysts for the production of sustainable kerosene.
Photo credit: Tiziana Carambia

The Federal Ministry of Education and Research (BMBF) is funding the international research project CARE-O-SENE (Catalyst Research for Sustainable Kerosene) with 30 million euros. It is intended to improve the production of sustainable kerosene on an industrial scale. For this purpose, the network partners, including the Karlsruhe Institute of Technology (KIT), are developing tailor-made catalysts to further develop the Fischer-Tropsch synthesis (FTS) established in fuel production for the use of renewable energy sources.

With a share of more than 80 percent, fossil fuels are still by far the most important raw material for fuels, heating and the chemical industry (source: International Energy Agency, IEA). Sustainable fuels are based on green hydrogen and carbon dioxide - and should make a significant contribution to decarbonizing sectors such as aviation, in which fossil fuels are particularly difficult to replace. In the CARE-O-SENE project, seven South African and German project partners are therefore researching next-generation Fischer-Tropsch catalysts.

Endangered fruit-eating animals play an outsized role in a tropical forest

A view of the Atlantic Forest in Brazil’s Rio de Janeiro state.
Credit: Adriano Gambarini/The Nature Conservancy

A new study by researchers at the University of Washington shows that losing a particular group of endangered animals — those that eat fruit and help disperse the seeds of trees and other plants — could severely disrupt seed-dispersal networks in the Atlantic Forest, a shrinking stretch of tropical forest and critical biodiversity hotspot on the coast of Brazil.

The findings, published Oct. 12 in the Proceedings of the Royal Society B, indicate that a high number of plant species in today’s Atlantic Forest rely on endangered frugivores — the scientific term for animals that eat primarily fruit — to help disperse their seeds throughout the forest. As a result, losing those endangered frugivores would leave a high proportion of plants without an effective means to disperse and regenerate — endangering these plants, reducing diversity in the Atlantic Forest and crippling critical portions of this ecosystem.

“Tropical forests contain this incredible diversity of trees,” said lead author Therese Lamperty, a UW postdoctoral researcher in biology. “One of the main processes forests use to maintain this diversity is dispersal. If you’re not dispersed, you’re in a crowd of trees that are just like you – all competing for resources. And there are a lot of plant enemies already in the area or that can be easily recruited, like harmful animals or plant diseases. Your chance of survival is higher when you get transported away from your mother tree to an area without trees like you.”

New study undermines the theory that depressed people are just more realistic

Photo credit: Hieu Van

Are depressed people simply more realistic in judging how much they control their lives, while others view the world through rose-colored lenses, living under the illusion that they have more control than they do?

That’s the general idea behind “depressive realism,” a theory that has held sway in science and popular culture for more than four decades.

The problem is, it’s just not true, new research finds.

“It’s an idea that exerts enough appeal that lots of people seem to believe it, but the evidence just isn’t there to sustain it,” says Professor Don Moore, the Lorraine Tyson Mitchell Chair in Leadership and Communication at UC Berkeley’s Haas School of Business and co-author of the study, in press at the journal Collabra:Psychology. “The good news is you don’t have to be depressed to understand how much control you have.”

Depressive realism

The concept of depressive realism stems from a 1979 study of college students examining whether they could predict how much control they had over whether a light turned green when they pushed a button. The original research concluded that the depressed students were better at identifying when they had no control over the lights, while those who weren’t depressed tended to overestimate their level of control.

U.S. Air Force Declares Initial Operational Capability of Sikorsky HH-60W Jolly Green II

The HH-60W Jolly Green II
Full Size Image
Credit: Lockheed Martin Corporation

The U.S. Air Force declared Initial Operational Capability (IOC) for the HH-60W Jolly Green II Combat Rescue Helicopter, validating the platform's operational readiness to forward deploy Air Force rescue crews around the globe. Sikorsky, a Lockheed Martin Company (NYSE: LMT) designed and manufactures the HH-60W, which enables the U.S. Air Force to conduct rescue missions at greater ranges and in the most challenging environments, and with increased survivability.

“This declaration is a vote of confidence from U.S. Air Force leadership and demonstrates the critical role of and need for the HH-60W,” said Nathalie Previte, vice president, Sikorsky Army & Air Force Systems. "Sikorsky is committed to continuing deliveries of the Department of Defense’s only dedicated combat search and rescue (CSAR) helicopter and to provide the most capable platform to rescue crews who depend on this aircraft day-in and day-out to conduct vital life-saving missions.”

Black Hole Spews Out Material Years After Shredding Star

Artist’s illustration of tidal disruption event AT2019dsg where a supermassive black hole spaghettifies and gobbles down a star. Some of the material is not consumed by the black hole and is flung back out into space. 
Resized Image using AI by SFLORG
Credit: DESY, Science Communication Lab

In October 2018, a small star was ripped to shreds when it wandered too close to a black hole in a galaxy located 665 million light years away from Earth. Though it may sound thrilling, the event did not come as a surprise to astronomers who occasionally witness these violent incidents while scanning the night sky.

But nearly three years after the massacre, the same black hole is lighting up the skies again — and it hasn’t swallowed anything new, scientists say.

“This caught us completely by surprise — no one has ever seen anything like this before,” says Yvette Cendes, a research associate at the Center for Astrophysics | Harvard & Smithsonian (CfA) and lead author of a new study analyzing the phenomenon.

The team concludes that the black hole is now ejecting material traveling at half of the speed of light, but are unsure why the outflow was delayed by several years. The results, described this week in the Astrophysical Journal, may help scientists better understand black holes’ feeding behavior, which Cendes likens to “burping” after a meal.

Viewing Earth from Space at Night: Tracking Our Changing Black Marble

Earth’s night lights as observed in 2016 based on NASA’s Black Marble Product.
Photo Credit: NASA

When the sun goes down and lights go on – or not — a multitude of data can be gathered by satellite from the night sky, giving insights into the dynamic human activities happening at the surface.

With remote sensing, things like land use changes, urban development, and forest management can be reliably and accurately measured by daylight. At nighttime, we can gather different kinds of data. One way to do this is with NASA’s Black Marble, a product suite that scans the sky each night and is powerful enough to sense all kinds of lights on the surface of Earth, from holiday lights to a single 12,000-lumen flashlight, from space.

However, the data gathered at night can be difficult to analyze says Department of Natural Resources and the Environment Assistant Professor and Director of the Global Environmental Remote Sensing (GERS) Laboratory Zhe Zhu. He explains nighttime satellite data can be influenced by many factors, which leads to a large degree of temporal variation, even for the well-calibrated NASA Black Marble data.

“The first time I looked at a time series of the data, I felt like it was almost impossible to use,” says Zhu.

A team of researchers from GERS including Zhu and NRE Ph.D. student Tian Li, along with researchers from NASA and the University of Maryland Earth System Science Interdisciplinary Center has developed a method that is capable of providing daily global moderate resolution nighttime light change maps. The results are published in the journal Remote Sensing of Environment.

Thirdhand smoke can trigger skin diseases

Skin is the largest organ to contact thirdhand smoke and may thus receive the greatest exposure

Thirdhand smoke, or THS, comprises the residual pollutants from tobacco smoke that remain on surfaces and in dust after tobacco has been smoked. It can remain on indoor surfaces indefinitely, causing potentially harmful exposure to both smokers and non-smokers.

A team led by researchers at the University of California, Riverside, has found that acute exposure of the skin to THS elevates biomarkers associated with the initiation of skin diseases, such as contact dermatitis and psoriasis.

“We found exposure of human skin to THS initiates mechanisms of inflammatory skin disease, and elevates urinary biomarkers of oxidative harm, which could lead to other diseases, such as cancer, heart disease, and atherosclerosis,” said Shane Sakamaki-Ching, a former graduate student at UC Riverside who graduated with a doctoral degree in cell, molecular, and developmental biology in March 2022. “Alarmingly, acute dermal exposure to THS mimics the harmful effects of cigarette smoking.”

The study, published in eBioMedicine of The Lancet family of journals, is the first to be performed on humans exposed dermally to THS.