No link between IVF-assisted conception and school-age childhood development outcomes

Researchers say the study offers important reassurance for clinicians and families.
Photo Credit: Yan Krukau

A comprehensive study of more than 400,000 children - with over 11,000 conceived via in-vitro fertilization (IVF) - has found no link between IVF conception and adverse developmental outcomes for school-age children.

Published today in PLOS Medicine, the study involved collaboration between the three major IVF units in Victoria - Melbourne IVF, Monash IVF and City Fertility Centre, and incorporated data on over 400,000 children born between 2005 and 2013, 11,059 of whom were conceived via IVF.

Led by Dr Amber Kennedy and Dr Anthea Lindquist, the study assessed childhood developmental and educational outcomes using the Australian Early Development Census (AEDC) and the National Assessment Program for Literacy and Numeracy (NAPLAN).

Dr Kennedy said: “We found no difference in performance across the five domains of the AEDC, nor in NAPLAN scores, between children who were born after IVF-assisted conception and those who were conceived without assistance.

Fish sensory organ key to improving navigational skills of underwater robots

Yellow blaze African cichlid
Photo Credit: Sarah Page

Scientists, led by the University of Bristol, have been studying a fish sensory organ to understand cues for collective behavior which could be employed on underwater robots.

This work was centered around the lateral line sensing organ in African cichlid fish, but found in almost all fish species, that enables them to sense and interpret water pressures around them with enough acuity to detect external influences such as neighboring fish, changes in water flow, predators and obstacles.

The lateral line system as a whole is distributed over the head, trunk and tail of the fish. It is comprised of mechanoreceptors (neuromasts) that are either within subdermal channels or on the surface of the skin.

Lead author Elliott Scott of the University of Bristol’s Department of Engineering Mathematics explained: “We were attempting to find out if the different areas of the lateral line - the lateral line on the head versus the lateral line on the body, or the different types of lateral line sensory units such as those on the skin, versus those under it, play different roles in how the fish is able to sense its environment through environmental pressure readings.

Interfering in big decisions friends and family take could violate a crucial moral right, philosopher argues

Two people speaking, sat at a table 
Photo Credit: Charles Deluvio

If you’ve told an adult friend or family member that they should not take a job, not date someone, not try skydiving or not move abroad, you may have violated a crucial moral right to ‘revelatory autonomy’ and ‘self-authorship’, according to a philosopher at Christ’s College, Cambridge.

Dr Farbod Akhlaghi’s study, published in the journal Analysis, is the first of its kind to suggest that we have a moral right to ‘revelatory autonomy’, that is the right to discover for ourselves who we’ll become as a result of making ‘transformative choices’, choices to have experiences that teach us what that experience will be like for us whilst also changing our core preferences, values and desires.

Dr Akhlaghi says: “The ability to see that the person we’ve become is the product of decisions that we made for ourselves is very important.

“I’m not telling people what to do. I’m just highlighting part of what is morally at stake in these very common interactions and trying to develop a framework for us to understand them. I hope some may find this helpful, as these will always be difficult moments for all of us.”

Global study of hypoxia in rivers shows it is more prevalent than previously thought

High-frequency sensors deployed in streams, such as those being installed by Joanna Blaszczak in a stream in Montana, can provide continuous data that captures night-time hypoxic conditions.
Photo Credit: Malgosia Blaszczak.

New research led by University of Nevada, Reno Assistant Professor Joanna Blaszczak shows hypoxia in rivers and streams is generally much more prevalent across the globe than previously thought. Hypoxia is low or depleted oxygen levels in surface waters that can be harmful to aquatic species and can in some cases increase production of harmful greenhouse gases from rivers.

The research, published recently in the journal Limnology and Oceanography Letters, compiles over 118 million readings of dissolved oxygen and temperature taken from over 125,000 locations in rivers across six continents and 93 countries and spanning over 100 years, from 1900 to 2018. Hypoxia, defined in this study as dissolved oxygen concentrations below 2 milligrams per liter, was detected in rivers and streams in 53 countries, with 12.6% of all locations exhibiting at least one hypoxic measurement.

“Hypoxia in coastal waters and lakes is widely recognized as a detrimental environmental issue, yet we have lacked a comparable understanding of hypoxia in rivers,” Blaszczak, with the University’s College of Agriculture, Biotechnology & Natural Resources, said. “While 12.6% might not seem like a huge percentage, previously it was generally thought that occurrences of hypoxia in rivers and streams were exceedingly rare. Having shown presence of hypoxia in one of every eight river locations with data is definitely a game changer in terms of how we need to think of and give attention to the issue of hypoxia in rivers and streams.”

Lockheed Martin Announces Successful First Flight Of F-16 Block 70 Aircraft

F-16 Block 70 first flight
Photo Credit: Lockheed Martin Corporation

Lockheed Martin today announced the successful first flight of the F-16 Block 70 at its Greenville, South Carolina site. 

The flight occurred Jan. 24 at 9:17 a.m. ET, with Lockheed Martin test pilots Dwayne "Pro" Opella and Monessa "Siren" Balzhiser at the helm. Total flight time was approximately 50 minutes and included airworthiness checks, such as engine, flight control and fuel system checks, as well as basic aircraft handling. 

"Today's successful flight is a testament of the hard work, dedication and commitment to our customers and their missions," said OJ Sanchez, vice president, Integrated Fighter Group, which includes the F-16 program. "This milestone demonstrates Lockheed Martin's commitment to advancing this program and getting this much-needed aircraft and its advanced 21st Century Security capabilities to the warfighter."

This F-16 Block 70 jet is the first of 16 jets to be delivered to Bahrain. Six countries have selected Block 70/72 aircraft. In addition to the current official backlog of 128 jets to-date to be built in Greenville, Jordan last year signed a Letter of Offer and Acceptance (LOA) for eight jets and last week signed an additional LOA for four more jets. Lockheed Martin has received a contract to begin Jordan's long-lead activities. Bulgaria has also signed an LOA for an additional eight jets for its fleet. Once these are finalized, the backlog will increase to 148.

Plasma thrusters used on satellites could be much more powerful

The chamber where prof. Benjamin Jorns’ team tests the new Hall plasma thruster at the PEPL lab on the University of Michigan’s North Campus.
Photo Credit: Marcin Szczepanski/Lead Multimedia Storyteller, University of Michigan College of Engineering

It was believed that running more propellant through a Hall thruster would wreck its efficiency, but new experiments suggest they might power a crewed mission to Mars

It was believed that Hall thrusters, an efficient kind of electric propulsion widely used in orbit, need to be large to produce a lot of thrust. Now, a new study from the University of Michigan suggests that smaller Hall thrusters can generate much more thrust—potentially making them candidates for interplanetary missions.

“People had previously thought that you could only push a certain amount of current through a thruster area, which in turn translates directly into how much force or thrust you can generate per unit area,” said Benjamin Jorns, U-M associate professor of aerospace engineering who led the new Hall thruster study to be presented at the AIAA SciTech Forum in National Harbor, Maryland, today.

Environment law fails to protect threatened species

The tiger quoll lost 82 per cent of its total referred habitat to projects considered unlikely to have a significant impact.
Photo Credit: JJ Harrison / Creative Commons Attribution-Share Alike 3.0 Unported

Federal environmental laws are failing to mitigate against Australia’s extinction crisis, according to University of Queensland research.

UQ PhD candidate Natalya Maitz led a collaborative project which analyzed potential habitat loss in Queensland and New South Wales and found the Environment Protection and Biodiversity Conservation 1999 (EPBC) Act is not protecting threatened species.

“The system designed to classify development projects according to their environmental impact is more or less worthless,” Ms. Maitz said.

“There’s no statistically significant difference between the amount of threatened habitat destroyed under projects deemed ‘significant’ or ‘not significant’ by the national biodiversity regulator.”

Under the EPBC Act, individuals or organizations looking to commence projects with a potentially ‘significant impact’ on protected species must seek further federal review and approval.

Traffic pollution impairs brain function

fMRI shows decreased functional connectivity in the brain following exposure to traffic pollution.
Image Credit: Courtesy of University of British Columbia

First-in-the-world study suggests that even brief exposure to air pollution has rapid impacts on the brain

A new study by researchers at the University of British Columbia and the University of Victoria has shown that common levels of traffic pollution can impair human brain function in only a matter of hours.

The peer-reviewed findings, published in the journal Environmental Health, show that just two hours of exposure to diesel exhaust causes a decrease in the brain’s functional connectivity – a measure of how different areas of the brain interact and communicate with each other. The study provides the first evidence in humans, from a controlled experiment, of altered brain network connectivity induced by air pollution.

“For many decades, scientists thought the brain may be protected from the harmful effects of air pollution,” said senior study author Dr. Chris Carlsten, professor and head of respiratory medicine and the Canada Research Chair in occupational and environmental lung disease at UBC. “This study, which is the first of its kind in the world, provides fresh evidence supporting a connection between air pollution and cognition.”

Researchers combine classical and quantum optics for super-resolution imaging

A conceptual rendering of the super-resolution experiment, which will be enabled by a grant from the Chan Zuckerberg Initiative.
Illustration Credit: Courtesy of Colorado State University

The ability to see invisible structures in our bodies, like the inner workings of cells, or the aggregation of proteins, depends on the quality of one’s microscope. Ever since the first optical microscopes were invented in the 17th century, scientists have pushed for new ways to see things more clearly, at smaller scales and deeper depths.   

Randy Bartels, professor in the Department of Electrical Engineering at Colorado State University, is one of those scientists. He and a team of researchers at CSU and Colorado School of Mines are on a quest to invent some of the world’s most powerful light microscopes – ones that can resolve large swaths of biological material in unimaginable detail.   

The name of the game is super–resolution microscopy, which is any optical imaging technique that can resolve things smaller than half the wavelength of light. The discipline was the subject of the 2014 Nobel Prize in Chemistry, and Bartels and others are in a race to keep circumventing that diffraction limit to illuminate biologically important structures inside the body.  

New DNA Biosensor Could Unlock Powerful, Low-Cost Clinical Diagnostics

In a new study, researchers demonstrate the capability of DNA biosensor components for a unique modular DNA biosensor. The researchers plan to integrate their design within a device the size and shape of a smartphone for low-cost clinical diagnostics. 
Illustration Credit: N. Hanacek/NIST

DNA can signal the presence of or predisposition to a slew of diseases, including cancer. The ability to flag down these clues, known as biomarkers, allows medical professionals to make critical early diagnoses and provide personalized treatments. The typical methods of screening can be laborious, expensive or limited in what they can uncover. A new biosensor chip that boasts an accurate and inexpensive design may increase accessibility to high-quality diagnostics. 

The biosensor, developed by researchers at the National Institute of Standards and Technology (NIST), Brown University and the French government-funded research institute CEA-Leti, identifies biomarkers by measuring how binding occurs between DNA strands and the device. What sets it apart from other similar sensors is its modular design, which lowers costs by making it easier to mass produce and allowing the most expensive components to be reused. 

In a paper just posted online from the latest IEEE International Electron Devices Meeting, the researchers presented results of a study that demonstrates the device’s high sensitivity and precision despite its modularity, which is typically associated with diminished performance.