. Scientific Frontline

Friday, April 14, 2023

Ambrosia beetles can recognize their food fungi by their scents

Nest of a black stem borer (Xylosandrus germanus) in a hazelnut branch with adult females (large), a male (small) and individual larvae. The greyish fungal coating of the food fungus is visible on the walls of the tunnel system.
Photo Credit: Antonio Gugliuzzo

Experiments at the University of Freiburg provide evidence for the first time of the ability of ambrosia beetles to distinguish between food and harmful fungi

Certain ambrosia beetles species engage in active agriculture. As social communities, they breed and care for food fungi in the wood of trees and ensure that so-called weed fungi spread less. Researchers led by Prof. Dr. Peter Biedermann, professor of Forest Entomology and Forest Protection at the University of Freiburg, now demonstrates for the first time that ambrosia beetles can distinguish between different species of fungi by their scents. "The results can contribute to a better understanding of why beetles selectively colonize trees with conspecifics and how exactly their fungiculture works," says Biedermann. "In addition, the scents of the fungi could be used to develop attractants to control non-native ambrosia beetles."

Curtin researchers map genetic signature of precursor to liver cancer

Photo Credit: Julia Koblitz

Researchers at Curtin University have identified the genetic signature of pre-malignant liver cells, offering potentially significant implications for the almost 3,000 Australians diagnosed with the deadly cancer each year.

The study, published in the prestigious journal Cell Genomics, found that quantifying pre-malignant liver cells in patients with liver disease could help determine their future risk of developing liver cancer.

First author Dr Rodrigo Carlessi, from the Curtin Medical School and the Curtin Health Innovation Research Institute, said the discovery had the potential to save lives by changing how chronic liver disease patients are staged and monitored based on their cancer risk.

“The research used cutting-edge technology to identify the molecular fingerprint of thousands of genes, one cell at a time,” Dr Carlessi said.

“During this process, we discovered the genetic signature and its diagnostic value, which was subsequently confirmed in several hundred individual patient liver samples.

Private pools are a major cause of water scarcity

The researchers found that city elites over-consume water for their own leisure activities, such as filling their pools, watering their gardens or washing their cars.
Photo Credit: Joe Ciciarelli

Rich elites with large pools and well-kept lawns deprive poorer groups of basic access to water in cities around the world. Social inequality is a major cause of urban water scarcity than environmental factors such as climate change or urban population growth. This shows a new study, led by Uppsala University and now published in Nature Sustainability.

"Our study shows that the only way to preserve available water resources is to change privileged lifestyles, limit the amount of water used for recreational purposes and distribute income and water resources more evenly. Future strategies for secure water supply and drought resistance must be more proactive and be able to identify and counteract long-term inequality and unsustainable patterns that create the type of water crisis in cities we saw in Cape Town," says Dr. Elisa Savelli at Uppsala University who led the study.

The study was conducted with colleagues at Vrije Universiteit Amsterdam in the Netherlands and the University of Manchester and the University of Reading in the United Kingdom. They have developed a model that analyzes how water is used by households in Cape Town, which in turn gives an understanding of how different classes of society consume water. They found that city elites over-consume water for their own leisure activities, such as filling their pools, watering their gardens or washing their cars.

How rainforest fish adapt to habitat

Eastern rainbowfish from the Wet Tropics region of Australia.
Photo Credit: Keith Martin.

The future of freshwater fish species in Australia’s tropical rainforest areas, including the Daintree and Mosman Gorge, will increasingly be subject to the vagaries of climatic and other changes.

Flinders University molecular ecology researchers have led an in-depth study of the colorful eastern rainbowfish for clues about how their populations have adapted to local conditions in the creeks and rivers of the wet tropical areas of Far North Queensland.

Their study, published in the Nature journal Heredity, provides insights into what drives genetic diversity in Australian eastern rainbowfish (Melanotaenia splendida splendida) – highlighting the ways their biodiversity may be affected, and conserved, particularly with any increase in climate change rates.

“Tropical rainforests are home to a staggering variety of plants and animals, ranking them among Earth’s greatest biodiversity hotspots,” says postdoctoral research fellow Dr Katie Gates, first author on the new paper.

Benefits of “Zombie” Cells: Senescent Cells Aid Regeneration in Salamanders

The salamander species studied by the Yun group: a red spotted newt Notophthalmus viridescens.
Photo Credit: Dr. Maximina Yun

Scientists show that so-called senescent cells, i.e., cells that have permanently stopped dividing, boost production of new muscle cells to enhance regeneration of lost limbs in salamanders.

Senescent cells, often referred to as "zombie" cells, have long been associated with aging and disease. However, a new study from the Center for Regenerative Therapies Dresden (CRTD) at TU Dresden adds to a growing body of evidence that not all senescent cells are harmful. The study led by Dr. Maximina Yun shows that these cells can play a beneficial role in regeneration. Her team found that senescent cells boost muscle formation in regenerating salamander limbs. Their findings reveal a new role for senescent cells and expand the understanding of the early events in the regeneration process. The research was published in the journal Aging Cell.

Senescent cells are cells that have permanently stopped dividing in response to cellular stress but have not died. As organisms age, the number of senescent cells in the body increases. This accumulation is currently considered one of the hallmarks of aging and has been linked to a variety of diseases, including cancer. However, the true nature of these cells may be more complex and context-dependent.

Thursday, April 13, 2023

Apes may have evolved upright stature for leaves, not fruit, in open woodland habitats

Artistic rendering of the open woodland habitat reconstruction at Moroto II with Morotopithecus bishopi vertically climbing with infant on back and juvenile below. Active volcano (Mount Moroto) is in background. Fossil relative of an elephant (Prodeinotherium) is foraging in center back.
Illustration Credit: Corbin Rainbolt

Anthropologists have long thought that our ape ancestors evolved an upright torso in order to pick fruit in forests, but new research from the University of Michigan suggests a life in open woodlands and a diet that included leaves drove apes’ upright stature.

The findings shed light on ape origins and push back the origin of grassy woodlands from between 7 million and 10 million years ago to 21 million years ago in equatorial Africa, during the Early Miocene.

Fruit grows on the spindly peripheries of trees. To reach it, large apes need to distribute their weight on branches stemming from the trunk, then reach out with their hands toward their prize. This is much easier if an ape is upright because it can more easily grab onto different branches with its hands and feet. If its back is horizontal, then its hands and feet are generally underneath the body, making it much harder to move outward to the smaller branches of a tree—especially if the ape is large bodied.

AI Tool Predicts Colon Cancer Survival, Treatment Response

New AI tool accurately predicts both overall survival and disease-free survival after colorectal cancer diagnosis.
Image Credit: bodymybody

A new artificial intelligence model designed by researchers at Harvard Medical School and National Cheng Kung University in Taiwan could bring much-needed clarity to doctors delivering prognoses and deciding on treatments for patients with colorectal cancer, the second deadliest cancer worldwide.

Solely by looking at images of tumor samples — microscopic depictions of cancer cells — the new tool accurately predicts how aggressive a colorectal tumor is, how likely the patient is to survive with and without disease recurrence, and what the optimal therapy might be for them.

Having a tool that answers such questions could help clinicians and patients navigate this wily disease, which often behaves differently even among people with similar disease profiles who receive the same treatment — and could ultimately spare some of the 1 million lives that colorectal cancer claims every year.

Study reveals how pollinators cope with plant toxins

Photo Credit: Dustin Humes

Pollinators such as honeybees produce special enzymes that detoxify defense chemicals produced by plants, new research shows.

Many plants produce alkaloids as protection against herbivores, and these toxins are also found in their nectar and pollen.

The new study, by the University of Exeter and Bayer AG, examined the genes of several species in a group called Hymenoptera – insects including bees, wasps, ants and sawflies that share a common ancestor about 280 million years ago.

Remarkably, all the species tested produce the same group of enzymes (the CYP336 family of cytochrome P450 enzymes) to tackle alkaloid toxins.

“These species differ greatly, but one thing they share is this ability to detoxify alkaloids,” said Dr Angie Hayward, from Exeter’s Penryn Campus in Cornwall.

Wednesday, April 12, 2023

Scientists develop new way to measure wind

Photo Credit: Zbynek Burival

Using data from two NOAA satellites, University of Arizona researchers developed an algorithm for measuring wind via water vapor.

Wind speed and direction provide clues for forecasting weather patterns. In fact, wind influences cloud formation by bringing water vapor together. Atmospheric scientists have now found a novel way of measuring wind – by developing an algorithm that uses data from water vapor movements. This could help predict extreme events like hurricanes and storms.

A study published by University of Arizona researchers in the journal Geophysical Research Letters provides, for the first time, data on the vertical distribution of horizontal winds over the tropics and midlatitudes. The researchers got the water vapor movement data by using two operational satellites of the National Oceanic and Atmospheric Administration, or NOAA, the federal agency for weather forecasting.

Wind brings everything else in the atmosphere together, including clouds, aerosols, water vapor, precipitation and radiation, said Xubin Zeng, co-author of the study and the director of the Climate Dynamics and Hydrometeorology Collaborative at UArizona. But it has remained somewhat elusive.

How did Earth get its water?

Stock photo

For decades, what researchers knew about planet formation was based primarily on our own Solar System. However, the explosion of exoplanet research over the past decade informed a new approach to modeling the Earth’s embryonic state.

Our planet’s water could have originated from interactions between the hydrogen-rich atmospheres and magma oceans of the planetary embryos that comprised Earth’s formative years, according to new work from Carnegie Science’s Anat Shahar and UCLA’s Edward Young and Hilke Schlichting. Their findings, which could explain the origins of Earth’s signature features, are published in Nature.

For decades, what researchers knew about planet formation was based primarily on our own Solar System. Although there are some active debates about the formation of gas giants like Jupiter and Saturn, it is widely agreed upon that Earth and the other rocky planets accreted from the disk of dust and gas that surrounded our Sun in its youth.

As increasingly larger objects crashed into each other, the baby planetesimals that eventually formed Earth grew both larger and hotter, melting into a vast magma ocean due to the heat of collisions and radioactive elements. Over time, as the planet cooled, the densest material sank inward, separating Earth into three distinct layers—the metallic core, and the rocky, silicate mantle and crust.

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