. Scientific Frontline

Tuesday, April 5, 2022

The global “plastic flood” reaches the Arctic

Collecting plastics after the catamaran.
Credit: Alfred-Wegener-Institute / Esther Horvath

Even the High North can’t escape the global threat of plastic pollution. An international review study just released by the Alfred Wegener Institute shows the flood of plastic has reached all spheres of the Arctic: large quantities of plastic - transported by rivers, the air and shipping- can now be found in the Arctic Ocean. High concentrations of microplastic can be found in the water, on the seafloor, remote beaches, in rivers, and even in ice and snow. Plastic is not only a burden for ecosystems; it could also worsen climate change. The study was just released in the journal Nature Reviews Earth & Environment.

The numbers speak for themselves. Today, between 19 and 23 million metric tons of plastic litter per year end up in the waters of the world – that’s two truckloads per minute. Since plastic is also very stable, it accumulates in the oceans, where it gradually breaks down into ever smaller pieces – from macro- to micro- and nanoplastic and can even enter the human bloodstream. And the flood of debris is bound to get worse: global plastic production is expected to double by 2045.

The consequences are serious. Today, virtually all marine organisms investigated – from plankton to sperm whales – come into contact with plastic debris and microplastic. And this applies to all areas of the world’s oceans – from tropical beaches to the deepest oceanic trenches. As the study published by the Alfred Wegener Institute, Helmholtz Centre for Polar and Marine Research (AWI) now shows, the High North is no exception. “The Arctic is still assumed to be a largely untouched wilderness,” says AWI expert Dr Melanie Bergmann. “In our review, which we jointly conducted with colleagues from Norway, Canada and the Netherlands, we show that this perception no longer reflects the reality. Our northernmost ecosystems are already particularly hard hit by climate change. This is now exacerbated by plastic pollution. And our own research has shown that the pollution continues to worsen.”

Flesh-eating bacteria in Ala Wai Canal could increase threefold by end of century

Field team casting off at the Ala Wai Harbor.
Photo credit: Brian Glazer, UH SOEST

Vibrio vulnificus, a “flesh-eating” bacterium that lives naturally in the water of the Ala Wai Canal in Waikīkī is likely to increase substantially in coming decades, but infections are rare. In recently published research, University of Hawaiʻi at Mānoa scientists highlight the potential for using oceanographic sensors to make accurate predictions of V. vulnificus. By assessing rainfall, water temperature, dissolved nutrients and organic matter the team can forecast potential spikes in levels of the bacteria.

V. vulnificus has been relatively understudied in tropical ecosystems and further, the implications of climate change for this and other coastal human pathogens are generally unknown.

The research team collaborated with the UH Strategic Monitoring and Resilience Training in the Ala Wai Watershed (SMART Ala Wai Program) where at least 20 undergraduate students and six graduate students from the UH Mānoa School of Ocean and Earth Science and Technology (SOEST) participated in sample collection from the canal and processing at the Daniel K. Inouye Center for Microbial Oceanography: Research and Education.

The art of smell: Research suggests the brain processes smell both like a painting and a symphony

What happens when we smell a rose? How does our brain process the essence of its fragrance? Is it like a painting – a snapshot of the flickering activity of cells – captured in a moment in time? Or like a symphony, an evolving ensemble of different cells working together to capture the scent? New research suggests that our brain does both.

“These findings reveal a core principle of the nervous system, flexibility in the kinds of calculations the brain makes to represent aspects of the sensory world,” said Krishnan Padmanabhan, Ph.D., an associate professor of Neuroscience and senior author of the study recently published in Cell Reports. “Our work provides scientists with new tools to quantify and interpret the patterns of activity of the brain.”

Researchers developed a model to simulate the workings of the early olfactory system – the network the brain relies on for smelling. Employing computer simulations, they found a specific set of connections, called centrifugal fibers, which carry impulses from other parts of the central nervous system to the early sensory regions of the brain, played a critical role. These centrifugal fibers act as a switch, toggling between different strategies to efficiently represent smells. When the centrifugal fibers were in one state, the cells in the piriform cortex – where the perception of an odor forms – relied on the pattern of activity within a given instant in time. When the centrifugal fibers were in the other state, the cells in the piriform cortex improved both the accuracy and the speed with which cells detected and classified the smell by relying on the patterns of brain activity across time.

These processes suggest the brain has multiple responses to representing a smell. In one strategy, the brain uses a snapshot, like a painting or a photograph, at a given moment to capture the essential features of the odor. In the other strategy, the brain keeps track of the evolving patterns. It is attuned to which cells turn on and off and when – like a symphony.

The dark matter of the brain

Electrical synapses connect neurons in almost all brains; however, little is known about them. A study now shows for the first time where these specific synapses occur in the fruit fly brain and that they influence the function and stability of nerve cells.
Credit: MPI for Biological Intelligence, i.f. / Julia Kuhl

They are part of the brain of almost every animal species, yet they remain usually invisible even under the electron microscope. "Electrical synapses are like the dark matter of the brain," says Alexander Borst, director at the MPI for Biological Intelligence, in foundation (i.f). Now a team from his department has taken a closer look at this rarely explored brain component: In the brain of the fruit fly Drosophila, they were able to show that electrical synapses occur in almost all brain areas and can influence the function and stability of individual nerve cells.

Neurons communicate via synapses, small contact points at which chemical messengers transmit a stimulus from one cell to the next. We may remember this from biology class. However, that is not the whole story. In addition to the commonly known chemical synapses, there is a second, little-known type of synapse: electrical synapse. "Electrical synapses are much rarer and are hard to detect with current methods. That's why they have hardly been researched so far," explains Georg Ammer, who has long been fascinated by these hidden cell connections. "In most animal brains, we therefore don't know even basic things, such as where exactly electrical synapses occur or how they influence brain activity."

Boeing’s Spectrolab to Power NASA’s Roman Space Telescope

Spectrolab, Inc., a wholly owned subsidiary of Boeing, will build the solar cells and integrate solar panels for NASA’s Roman Space Telescope.
Credit: GSFC/SVS

Spectrolab, Inc., a wholly owned subsidiary of Boeing [NYSE: BA], will manufacture, integrate and test approximately 4,000 XTJ Prime solar cells for NASA’s Nancy Grace Roman Space Telescope.

“Using Spectrolab’s XTJ Prime solar cells, NASA will be able to maximize the Roman Space Telescope’s power generation, allowing greater data gathering capability while operating in a unique mission environment at the L2 Lagrange point,” said Tony Mueller, president of Spectrolab. “These cells leverage both heritage and high efficiency for the agency’s newest universe studying telescope.”

Spectrolab’s NeXt Triple Junction (XTJ) Prime solar cells will provide power to the telescope, including its two main instruments – the Wide Field Instrument and the Coronagraph Instrument – as well as the primary mirror that is 2.4 meters in diameter (7.9 feet), and is the same size as the Hubble Space Telescope's primary mirror. The solar array consists of six panels, each approximately 3m-by-2.5m and consists of 4,000 triple junction solar cells. Triple junction solar cells leverage multiple bandgaps tuned to different wavelengths of the solar spectrum, allowing higher efficiencies not possible with commercially available silicon solar cell technology.

Historic Hypersonic Flight

Artist rendering of the Hypersonic Air-breathing Weapon Concept (HAWC), the result of a partnership between the Defense Advanced Research Projects Agency, Air Force Research Lab, Lockheed Martin and Aerojet Rocketdyne.
Credit: Lockheed Martin Corporation

The Defense Advanced Research Projects Agency (DARPA), Air Force Research Lab (AFRL), Lockheed Martin (NYSE: LMT) and Aerojet Rocketdyne (NYSE: AJRD) team successfully flight tested the Hypersonic Air-breathing Weapon Concept (HAWC). This historic flight reached speeds in excess of Mach 5, altitudes greater than 65,000 feet and furthers the understanding of operations in the high-speed flight regime.

"Our work with DARPA and AFRL on the HAWC program demonstrates that air-breathing hypersonic systems are a cost-effective solution to address rapidly emerging threats in the global security arena," said John Clark, vice president and general manager Lockheed Martin Skunk Works®. "The success of this flight test is evidence that a strong partnership between government and industry is key to solving our nation's most difficult challenges and enabling new capabilities to counter threats to U.S. and allied forces."

Evidence Shows Violent Collapse Responsible for Formation of Jupiter-Like Protoplanet

This is an artist's illustration of a massive, newly forming exoplanet called AB Aurigae b. Researchers used new and archival data from the Hubble Space Telescope and the Subaru Telescope to confirm this protoplanet is forming through an intense and violent process, called disk instability.
Credits: NASA, ESA, Joseph Olmsted (STScI)

NASA's Hubble Space Telescope has directly photographed evidence of a Jupiter-like protoplanet forming through what researchers describe as an "intense and violent process." This discovery supports a long-debated theory for how planets like Jupiter form, called "disk instability."

The new world under construction is embedded in a protoplanetary disk of dust and gas with distinct spiral structure swirling around, surrounding a young star that's estimated to be around 2 million years old. That's about the age of our solar system when planet formation was underway. (The solar system's age is currently 4.6 billion years.)

"Nature is clever; it can produce planets in a range of different ways," said Thayne Currie of the Subaru Telescope and Eureka Scientific, lead researcher on the study.

Tuesday, March 29, 2022

In the heat of the wound

Empa researcher Fei Pan is working on a membrane made of nanofibers that releases medication only when the material heats up. Such a membrane could, for example, become active in a bandage as soon as inflammation starts.
Image: Empa

A bandage that releases medication as soon as an infection starts in a wound could treat injuries more efficiently. Empa researchers are currently working on polymer fibers that soften as soon as the environment heats up due to an infection, thereby releasing antimicrobial drugs.

It is not possible to tell from the outside whether a wound will heal without problems under the dressing or whether bacteria will penetrate the injured tissue and ignite an inflammation. To be on the safe side, disinfectant ointments or antibiotics are applied to the wound before the dressing is applied. However, these preventive measures are not necessary in every case. Thus, medications are wasted and wounds are over-treated.

Even worse, the wasteful use of antibiotics promotes the emergence of multi-resistant germs, which are an immense problem in global healthcare. Empa researchers at the two Empa laboratories Biointerfaces and Biomimetic Membranes and Textiles in St. Gallen wants to change this. They are developing a dressing that autonomously administers antibacterial drugs only when they are really needed.

The idea of the interdisciplinary team led by Qun Ren and Fei Pan: The dressing should be "loaded" with drugs and react to environmental stimuli. "In this way, wounds could be treated as needed at exactly the right moment," explains Fei Pan. As an environmental stimulus, the team chose a well-known effect: the rise in temperature in an infected, inflamed wound.

Invading Hordes of Crazy Ants May Have Finally Met Their Kryptonite

 

Tawny crazy ants swarm on a cobweb spider.
Credit: Mark Sanders.

When tawny crazy ants move into a new area, the invasive species is like an ecological wrecking ball — driving out native insects and small animals and causing major headaches for homeowners. But scientists at The University of Texas at Austin have good news, as they have demonstrated how to use a naturally occurring fungus to crush local populations of crazy ants. They describe their work this week in the journal Proceedings of the National Academy of Sciences.

“I think it has a lot of potential for the protection of sensitive habitats with endangered species or areas of high conservation value,” said Edward LeBrun, a research scientist with the Texas Invasive Species Research Program at Brackenridge Field Laboratory and lead author of the study.

In some parts of Texas, homes have been overrun by ants that swarm breaker boxes, AC units, sewage pumps and other electrical devices, causing shorts and other damage. Natives of South America, tawny crazy ants have raised alarm bells as they’ve spread across the southeastern U.S. during the past 20 years. The idea for using the fungal pathogen came from observing wild populations of crazy ants becoming infected and collapsing without human intervention.

“This doesn’t mean crazy ants will disappear,” LeBrun said. “It’s impossible to predict how long it will take for the lightning bolt to strike and the pathogen to infect any one crazy ant population. But it’s a big relief because it means these populations appear to have a lifespan.”

Other study authors are Rob Plowes and Lawrence Gilbert at Brackenridge Field Laboratory, and Melissa Jones formerly of the Texas Parks and Wildlife Department.

New method purifies hydrogen from heavy carbon monoxide mixtures

Chris Arges (right), Penn State associate professor of chemical engineering, proposes using high-temperature proton-selective polymer electrolyte membranes, or PEMs, to separate hydrogen from other gases in an ACS Energy Letters paper. Co-author Deepra Bhattacharya, Penn State doctoral student in chemical engineering, is seen at left.
Credit: Kelby Hochreither/Penn State.

Refining metals, manufacturing fertilizers and powering fuel cells for heavy vehicles are all processes that require purified hydrogen. But purifying, or separating, that hydrogen from a mix of other gases can be difficult, with several steps. A research team led by Chris Arges, Penn State associate professor of chemical engineering, demonstrated that the process can be simplified using a pump outfitted with newly developed membrane materials.

The researchers used an electrochemical hydrogen pump to both separate and compress hydrogen with an 85% recovery rate from fuel gas mixtures known as syngas and 98.8% recovery rate from conventional water gas shift reactor exit stream — the highest value recorded. The team detailed their approach in ACS Energy Letters.

Traditional methods for hydrogen separations employ a water gas shift reactor, which involves an extra step, according to Arges. The water gas shift reactor first converts carbon monoxide into carbon dioxide, which is then sent through an absorption process to separate the hydrogen from it. Then, the purified hydrogen is pressurized using a compressor for immediate use or for storage.

Fuel from waste wood

In collaboration with the Lappeenranta-Lahti University of Technology (LUT) in Finland, researchers at the Straubing Campus for Biotechnology and Sustainability of the Technical University of Munich (TUM) have developed a new process for the production of ethanol.
Image: Maria Schießl / TUM

According to the latest assessment report from the Intergovernmental Panel on Climate Change, a considerable reduction in CO2 emissions is required to limit the consequences of climate change. Producing fuel from renewable sources such as waste wood and straw or renewable electricity would be one way to reduce carbon emissions from the area of transportation. This is an area which is being addressed by researchers at the Technical University of Munich (TUM).

Ethanol is usually produced through the fermentation of sugars from starchy raw materials such as corn, or from lignocellulosic biomass, such as wood or straw. It is an established fuel that decarbonizes the transportation sector and can be a building block to reduce emissions of CO2 over the long term. In collaboration with the Lappeenranta-Lahti University of Technology (LUT) in Finland, researchers at the Straubing Campus for Biotechnology and Sustainability of the Technical University of Munich (TUM) have developed a new process for the production of ethanol.

Accelerated biological aging may cause bowel cancer

Scientists have shown how accelerated biological aging measured by an epigenetic clock may increase the risk of bowel cancer, according to a report published today in eLife.

The study provides evidence that biological age might play a causal role in the increased risk of certain diseases, and paves the way for interventions that could slow down this process.

Epigenetic markers are changes to DNA which may alter the way in which our genes work and are known to vary as we age. A type of epigenetic marker called DNA methylation is often used to measure age. DNA methylation patterns on the genome have been shown to relate closely with age and they can provide insights into 'biological aging' – that is, how old our cells look compared to how old they are in years.

“When an individual’s biological age is older than their chronological age, they are said to be experiencing epigenetic age acceleration,” explains first author Fernanda Morales-Berstein, a Wellcome Trust PhD Student in Molecular, Genetic and Lifecourse Epidemiology at the MRC Integrative Epidemiology Unit, University of Bristol. “Epigenetic age acceleration, as measured by DNA methylation-based predictors of age called epigenetic clocks have been associated with several adverse health outcomes including cancer. But although epigenetics can be used to predict cancer risk or detect the disease early, it is still unclear whether accelerated epigenetic aging is a cause of cancer.”

When maggots uncover a murder

These maggots belong to the latrine fly. They are quasi criminal officers.
Credit: Roberto Schirdewahn

Investigators still have to go in search of traces. But if they find crawling animals at the scene, they can be of great help to them.

First come the blowflies. A few hours after death, they control the eyes, nose, mouth and wounds of a lifeless body. Here they lay their eggs - and just a few days later it is teeming with life: numerous maggots hatch and feed on the dead tissue until they finally become new flies. Not only gliding, other types of flies join in over time, and finally various beetles are crawled on. The hustle and bustle that takes place on corpses can be quite revealing - for example, if you want to find out when and under what circumstances a person died.

With these questions, Dr. Ersin Karapazarlioglu is only too good. He conducts research in the RUB Faculty of Biology and Biotechnology in the Prof. Dr. Wolfgang Kirchner. Before coming to Germany in 2020, he worked for 17 years in Turkey as a criminal officer and as a lecturer at the police college and a university. He always looked for insects at crime scenes. With their help, he was able to determine the time of death of a body more precisely than with other methods. The method is called forensic entomology. The method was initially established in the USA and is still in its infancy in Europe.

Monday, March 28, 2022

Scorpions’ venomous threat to mammals a relatively new evolutionary step

Prashant Sharma displays a scorpion in a container
Credit: University of Wisconsin–Madison

Despite their reputation as living fossils, scorpions have remained evolutionarily nimble — especially in developing venom to fend off the rise of mammal predators. A new genetic analysis of scorpions’ toxin-making reveals recent evolutionary steps and may actually be a boon for researchers studying scorpion venom’s benefits to human health.

An international team of researchers led by University of Wisconsin–Madison biologists has assembled the largest evolutionary tree of scorpions yet, showing seven independent instances in which, the distinctive eight-legged creatures evolved venom compounds toxic to mammals.

“The last major changes to their body shape, their morphology, happened about 430 million years ago, when they left the water and moved onto land,” says Carlos Santibáñez-López, a former postdoctoral researcher at UW–Madison and lead author of the new study published today in the journal Systematic Biology. “But we know now that they have evolved in very important ways much more recently.”

Solar energy explains fast yearly retreat of Antarctica’s sea ice

A research vessel in Antarctica on June 3, 2017, the first day researchers saw the sun rise above the horizon after weeks of polar darkness. New research shows that solar radiation drives the relatively fast annual retreat of sea ice around Antarctica at the end of each calendar year.
Credit: Ben Adkison

In the Southern Hemisphere, the ice cover around Antarctica gradually expands from March to October each year. During this time the total ice area increases by 6 times to become larger than Russia. The sea ice then retreats at a faster pace, most dramatically around December, when Antarctica experiences constant daylight.

New research led by the University of Washington explains why the ice retreats so quickly: Unlike other aspects of its behavior, Antarctic Sea ice is just following simple rules of physics.

The study was published March 28 in Nature Geoscience.

“In spite of the puzzling longer-term trends and the large year-to-year variations in Antarctic Sea ice, the seasonal cycle is really consistent, always showing this fast retreat relative to slow growth,” said lead author Lettie Roach, who conducted the study as a postdoctoral researcher at the UW and is now a research scientist at NASA and Columbia University. “Given how complex our climate system is, I was surprised that the rapid seasonal retreat of Antarctic Sea ice could be explained with such a simple mechanism.”

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