Taking dinosaurs’ temperature with a new biomarker

Allosaurus bone extracellular matrix: microscopic view of bone soft tissues of one of the dinosaur specimens (Allosaurus) that were investigated for metabolic signals (metabolic crosslinks) in the fossilization products of the proteinaceous bone matrix. Fossilization introduces additional crosslinks that, in combination with metabolic crosslinks, generate the characteristic brown color of the fossil extracellular matrix which holds bone cells and blood vessels in place. The extracellular matrix also holds the crystalline, white bone mineral, apatite, in place.
Credit: J. Wiemann

A Yale-led research team has turned up the heat on dinosaur metabolism — establishing that the earliest dinosaurs and pterosaurs had exceptionally high metabolic rates and were warm-blooded animals.

The findings, published May 25 in the journal Nature, also show that dinosaurs’ metabolism did not decide their fate after an asteroid strike wiped out most animal species on the planet 65 million years ago.

“While modern ecologists tend to emphasize the importance of metabolic rate to ensure that animals survive environmental perturbations, we showed that metabolism is not the reason why birds were the only group of dinosaurs to survive the mass extinction event at the end of the Cretaceous period,” said lead author Jasmina Wiemann, a former Yale paleontologist who is now at CalTech. “Many dinosaurs with metabolisms as efficient as those in modern birds went extinct.”

Lunar cycle triggers Hawaiian box jellyfish to spawn on Oʻahu shores

Lead author Angel Yanagihara with Hawaiian Box Jellyfish.
Photo credit: Keoki Stender

A key number of hours of darkness during the lunar cycle triggers mature Hawaiian box jellyfish (Alatina alata) to swim to leeward shores on Oʻahu to spawn. That’s according to a published study in the journal ScienceDirect comprising more than a decade of work by a cross-disciplinary team of University of Hawaiʻi at Mānoa researchers.

Led by Angel Yanagihara, associate research professor at the UH Mānoa School of Ocean and Earth Science and Technology (SOEST) and the John A. Burns School of Medicine, UH Mānoa researchers have been carefully tracking local box jellyfish for more than 20 years. While the monthly shoreline aggregations are understood to occur like clockwork 8–10 days after each full moon, with jelly forecasts included on the local news, mysteries have remained: Why are they appearing at this particular part of the lunar cycle? Where do these box jellyfish come from and where are they found in the rest of the lunar cycle? Why has this become a monthly problem in only the last 30 years?

Combining biology, oceanography

With the new study, the team provided in-depth answers based upon cutting-edge oceanographic approaches including nightlong offshore vessel tracking, computer modeling of local currents and side scan sonar, as well as fundamental field ecology methods and anatomical microscopy.

Silk layer improves function of surgical masks

UC researchers studied the effectiveness of surgical masks in combination with a silk face mask. Biology student Adam Parlin, now with SUNY-ESF, examined the properties of silk in a UC biology lab.
Photo/Joseph Fuqua II/UC Creative + Brand

University of Cincinnati researchers found that a double layer of silk in combination with a surgical mask can enhance its ability to prevent the spread of viruses like COVID-19.

UC biologist Patrick Guerra, UC biologist Theresa Culley, UC postdoctoral researcher Adam Parlin, now at SUNY-ESF, and UC graduate student Samuel Stratton, now at the University of Michigan, began investigating silk as an alternative face mask material at the start of the COVID-19 pandemic in 2020 when personal protective equipment such as the N95 face mask was in short supply.

UC researchers found that double masking with a silk face mask also helps prolong the life of surgical masks without impeding a person's ability to breathe comfortably.

The study was published in the journal Aerosol and Air Quality Research.

Does herpes simplex virus change during transmission?

A new study offers clues as to how herpes simplex virus (HSV) genetic diversity is shared between transmission partners. The authors used viral genome sequencing to follow oral and genital samples of HSV, collected over a year of each partner's infection. Often, the same viral variants were observed in both partners within a transmission pair. Occasionally these variants developed into viral genome differences between partners. This is the first study to compare HSV-1 genomes between adult sexual transmission partners. Image created with BioRender.com.
Credit: Moriah Szpara, Penn State / Penn State

A new study helps explain how the virus that causes herpes might change during transmission between partners and over time during a long-term infection within a human host, which could have implications for future treatment strategies. The study, by a team of researchers from Penn State and the University of Washington, is the first to track genetic differences of the herpes simplex virus (HSV-1) as it moves between adult sexual transmission partners. Their findings revealed that viral population movement between partners has a strong impact on whether genetic differences appear at the start of new infections.

A paper describing this work appears online in the journal PLoS Pathogens.

“Hundreds of minor differences in the genome of HSV-1 have been documented around the world, and many of these differences — called variants — can be detected within a single human host,” said Molly Rathbun, graduate student in biochemistry and molecular biology at Penn State and the lead author of the paper. “How often these variants are transmitted and how quickly they evolve within a person has remained elusive until now. Improving our understanding of these processes might help us understand why individuals vary so much in the severity and frequency of their symptoms.”

Climate change on course to hit U.S. Corn Belt especially hard

Climate change will make the U.S. Corn Belt unsuitable for cultivating corn by 2100 without major technological advances in agricultural practices, an Emory University study finds.

Environmental Research Letters published the research, which adds to the evidence that significant agricultural adaptation will be necessary and inevitable in the Central and Eastern United States. It is critical that this adaptation includes diversification beyond the major commodity crops that now make up the bulk of U.S. agriculture, says Emily Burchfield, author of the study and assistant professor in Emory’s Department of Environmental Sciences.

“Climate change is happening, and it will continue to shift U.S. cultivation geographies strongly north,” Burchfield says. “It’s not enough to simply depend on technological innovations to save the day. Now is the time to envision big shifts in what and how we grow our food to create more sustainable and resilient forms of agriculture.”

Burchfield’s research combines spatial-temporal social and environmental data to understand the future of food security in the United States, including the consequences of a changing climate.

Pets or threats? Goldfish might be harmful for biodiversity

Invasive species are one of the leading causes of global biodiversity loss, and the pet trade is responsible for a third of all aquatic invasive species. Pet owners releasing unwanted pets into the wild is a major problem. Whilst many believe this is a humane option, new research suggests that attempting to ‘save’ the life of a goldfish could in fact lead to catastrophic outcomes for native biodiversity.

To better understand the ecological risks posed by species within the pet trade, the researchers focused on the two most commonly traded fish species in Northern Ireland: goldfish and the white cloud mountain minnow.

The globally popular goldfish was first domesticated over a thousand years ago and has since established non-native populations around the world. The white cloud mountain minnow on the other hand is a species with a limited invasion history to date.

Koalas exposed to double whammy health threat

Credit: Tara Gatehouse

An AIDS-like virus that is plaguing Australia’s koala population is leaving them more vulnerable to chlamydia and other threatening health conditions, University of Queensland research has found.

One of UQ’s leading COVID-19 vaccine researchers, Associate Professor Keith Chappell, has discovered that the chlamydia epidemic plaguing endangered koala populations in Queensland and NSW is linked to a common virus that likely suppresses koalas’ immune systems.

Dr Chappell and Dr Michaela Blyton, from UQ’s Australian Institute for Bioengineering and Nanotechnology and School of Chemistry and Molecular Biosciences, made this discovery after studying more than 150 koalas admitted to Currumbin Wildlife Hospital.

Dr Chappell said this study could have far reaching impacts and lead to better protective measures like breeding programs and new anti-viral medications.

“We know Queensland and NSW koala populations are heavily impacted by chlamydia infections and a retrovirus, but until now a clear link between the two has not been conclusively established,” Professor Chappell said.

“Our research has found that the amount of retrovirus circulating within an animal’s blood was strongly associated with chlamydia and symptoms like cystitis and conjunctivitis, as well as overall poor health.

“It’s a double whammy for already-endangered koalas.”

Secret to treating ‘Achilles’ heel’ of alternatives to silicon solar panels revealed

Solar panels 
Credit: Alachua County

The researchers used a combination of techniques to mimic the process of aging under sunlight and observe changes in the materials at the nanoscale, helping them gain new insights into the materials, which also show potential for optoelectronic applications such as energy-efficient LEDs and X-ray detectors, but are limited in their longevity.

Their results, reported in the journal Nature, could significantly accelerate the development of long-lasting, commercially available perovskite photovoltaics.

Perovksites are abundant and much cheaper to process than crystalline silicon. They can be prepared in liquid ink that is simply printed to produce a thin film of the material.

While the overall energy output of perovskite solar cells can often meet or – in the case of multi-layered ‘tandem’ devices – exceed that achievable with traditional silicon photovoltaics, the limited longevity of the devices is a key barrier to their commercial viability.

A typical silicon solar panel, like those you might see on the roof of a house, typically lasts about 20-25 years without significant performance losses.

Building a Pipeline of Space Cyber Defenders

Source/Credit: Pacific Northwest National Laboratory

Cybercrime is a growing threat to critical space-based technologies—from the satellites that feed communication devices to the global positioning systems that enable military operations. And as the United States continues to expand capabilities in space, the need to secure and protect space-based assets from hackers and other malicious actors has never been greater.

But finding cybersecurity professionals is tough. Currently, there are 600,000 open cybersecurity jobs in the United States, but only enough qualified workers to fill 400,000 of them. This deep shortage of cybersecurity talent not only puts a strain on employers, but it leaves crucial digital systems—both on Earth and in space—vulnerable to cyberattacks.

In an effort to grow the cybersecurity workforce needed to build more resilient and secure space systems, Pacific Northwest National Laboratory (PNNL) has teamed up with U.S. Space Force’s Space Systems Command to create the Cyber Halo Innovation Research Program—or CHIRP.

AI reveals unsuspected math underlying search for exoplanets

Artist’s concept of a sun-like star (left) and a rocky planet about 60% larger than Earth in orbit in the star’s habitable zone. Gravitational microlensing has the ability to detect such planetary systems and determine the masses and orbital distances, even though the planet itself is too dim to be seen. 
Image credit: NASA Ames/JPL-Caltech/T. Pyle

Artificial intelligence (AI) algorithms trained on real astronomical observations now outperform astronomers in sifting through massive amounts of data to find new exploding stars, identify new types of galaxies and detect the mergers of massive stars, accelerating the rate of new discovery in the world’s oldest science.

But AI, also called machine learning, can reveal something deeper, University of California, Berkeley, astronomers found: unsuspected connections hidden in the complex mathematics arising from general relativity — in particular, how that theory is applied to finding new planets around other stars.

In a paper appearing this week in the journal Nature Astronomy, the researchers describe how an AI algorithm developed to more quickly detect exoplanets when such planetary systems pass in front of a background star and briefly brighten it — a process called gravitational microlensing — revealed that the decades-old theories now used to explain these observations are woefully incomplete.

‘Beam Me Up:’ Nation’s First Quantum Drone Provides Unrivaled Security

Hacked bank and Twitter accounts, malicious power outages and attempts to tamper with medical records threaten the security of the nation’s health, money, energy, society and infrastructure. Harnessing the laws of nature – namely quantum physics – cutting–edge teleportation technology is taking cybersecurity to new, “unhackable” heights using miniscule particles of light or “beams.”

Florida Atlantic University’s Warner A. Miller, Ph.D., in concert with Qubitekk and L3Harris, is leading the United States’ efforts to deliver the first drone-based, mobile quantum network to seamlessly maneuver around buildings, inclement weather and terrain and quickly adapt to changing environments such as warfare.

Together with Qubitekk, an award-winning leader in manufacturing entangled photon sources and other hardware for networking quantum processors and sensors, FAU has been entrusted by the U.S. Office of the Secretary of Defense to develop the project.

The network includes a ground station, drones, lasers and iber optics to share quantum-secured information. Today’s telecommunication networks use fiber optics, connected by laser beams from the ground and between planes and satellites — called fiber and free space optical networks. Drones are used to save lives, secure infrastructure, help the environment and thwart hostile military advances such as the war between Russia and Ukraine.

Population-scale study highlights ongoing risk of COVID-19 in some cancer patients despite vaccination

Illustration of the coronavirus
Credit: Gerd Altmann

A study co-led by the Universities of Oxford, Birmingham and Southampton and the UK Health Security Agency (UKHSA), published in Lancet Oncology today by the UK Coronavirus Cancer Evaluation Project, has found that while COVID-19 vaccination is effective in most cancer patients, the level of protection against COVID-19 infection, hospitalization and death offered by the vaccine is less than in the general population and vaccine effectiveness wanes more quickly.

Dr Lennard Lee, Department of Oncology, University of Oxford who led the study said: ‘We know that people with cancer have a higher risk of severe COVID-19 disease and that the immune response in cancer patients following COVID-19 vaccination is lower. However, no study has looked at vaccine effectiveness and its waning in cancer patients at a population level. We have undertaken the largest real-world health system evaluation of COVID-19 in cancer patients globally.’

This study analyzed 377,194 individuals with active or recent cancer who had received two doses of the COVID-19 vaccine and undergone a SARS-CoV-2 PCR test in England. The numbers of breakthrough COVID-19 infections and COVID-19-associated hospitalizations and deaths in this cohort of cancer patients were compared to a control population without active or recent cancer.

New tool measures atomic scale defects, identifies transistor limitations

Engineering science and mechanics doctoral student Fedor Sharov adjusts settings in a very low frequency EDMR spectrometer.
Credit: Kelby Hochreither/Penn State

A new technique for studying defects in semiconductor materials could lead to improved speed, power and performance of electronic devices by revealing the atomic-level limitations of advanced materials.

Developed by a Penn State-led team of researchers and lead by former Penn State graduate student James Ashton, the analytic tool makes use of extremely small magnetic fields and frequencies far smaller than those typically used in such measurements to detect and measure imperfections in new materials, providing structural information about the magnetic interactions between electrons and nearby magnetic nuclei in a simpler way than previously possible.

The approach was published as a cover article in Applied Physics Letters. According to Patrick Lenahan, distinguished professor of engineering science and mechanics at Penn State and Ashton’s doctoral thesis adviser, the tool allows researchers to take a big step toward solving a variety of faults in next-generation devices.

New countermeasure against unwanted wireless surveillance

The intelligent reflective surface IRShield is positioned next to a Wi-Fi router to disguise the environment-dependent radio channel.
Credit: CASA, Michael Schwettmann

Wirelessly functioning devices are now omnipresent. However, wireless communication endangers privacy: passive eavesdroppers can access sensitive data through intercepted high-frequency signals.

Smart devices should make our everyday life easier. At the same time, however, they are a gateway for passive eavesdropping. In order to prevent possible monitoring of the movement profile in your own four walls, researchers from the Max Planck Institute for Security and Privacy, the Horst Görtz Institute for IT Security at the Ruhr University Bochum and the Technical University of Cologne have a new system developed to protect privacy in wireless communication. The researchers will present the process, based on the technology of intelligent reflective surfaces, on 24. May 2022 at the IEEE Symposium on Security and Privacy.

Reducing TV viewing to less than one hour a day could help prevent more than one in ten cases of coronary heart disease

Credit: yousafbhutta

In a study published today in BMC Medicine, researchers at the Medical Research Council (MRC) Epidemiology Unit show that – assuming a causal link – 11% of cases of coronary heart disease could be prevented if people watched less than an hour of TV each day.

According to the British Heart Foundation, coronary heart disease is one of the UK’s leading causes of death, responsible for around 64,000 deaths each year. In the UK, one in eight men and one in 15 women die from the disease. People with coronary heart disease are twice as likely to have a stroke.

One of the major risk factors for coronary heart disease is sedentary behavior – in other words, sitting for long periods of time rather than being physically active. To examine the link between time spent in screen-based sedentary behaviors such as TV viewing and leisure-time computer use, an individual’s DNA, and their risk of coronary heart disease, researchers examined data from the UK Biobank, a biomedical database and research resource containing anonymized genetic, lifestyle and health information from half a million UK participants.