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| According to the biologist, the production of lanolin ointment with extracts of tinder mushrooms does not require high costs. Photo Credit: UrFU press service |
UrFU biologists have identified the beneficial properties of tinder mushrooms. They found that an ointment based on lanolin and extracts from tinder helps heal wounds faster after burns, even third-degree burns that form scars. The ointment also reduces inflammation. The results of tests on rats were published in Bulletin of Siberian Medicine scientific journal.
“In order for the wound to heal, it is necessary not only to repair the cells but also the intercellular substance – the skin framework. This long process occurs in several stages. If this process is delayed, negative consequences may occur, such as severe inflammation or scarring. Lanolin-based ointments with tinder mushroom extracts promote the formation of new cells and reduce inflammation, which in turn accelerates the healing process,” said Alexander Ermoshin, Head of the Laboratory of Molecular and Cellular Biotechnology.
When creating the ointment, biologists used two types of mushrooms - Ganoderma applanatum and Fomitopsis pinicola - that were collected in the forests of the Sverdlovsk region. Researchers are confident that ointments containing mushroom extracts are safe for human use, as mushrooms have been used in traditional Chinese medicine and cosmetology for over 2,000 years. These mushrooms contain a large number of metabolites that have anti-inflammatory, anti-tumor, and immune-modulating effects.
“Ganoderma applanatum and Fomitopsis pinicola produce a unique complex of bioactive substances - polysaccharides, polyphenols and terpenes - which probably provide the wound healing effect,” stressed Irina Petrova, Senior Lecturer at the Faculty of Biology and Fundamental Medicine.
In wounds that were treated with mushroom ointment, scientists found a high number of fibroblasts. These cells play a crucial role in wound healing and skin regeneration, as well as maintaining youthful skin and reducing inflammation.
The scientists plan to patent the ointment. The low cost of producing such ointments could provide treatment for patients in countries with high rates of injury or in regions with limited medical resources. At the same time, the results obtained open up opportunities for creating effective wound healing agents that could be used not only for treating burns, but also for other types of skin injuries.
Published in journal: Bulletin of Siberian Medicine
Authors: I. M. Petrova, A. A. Ermoshin, and S. L. Khatsko
Source/Credit: Ural Federal University | Anastasia Pyankova
Reference Number: btech102925_01
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