Concordia researchers identify key marker linking coronary artery disease to cognitive decline

Zacharie Potvin-Jutras, with Claudine Gauthier:
“Our goal is to examine conditions at the onset of a heart disease, before there has been any significant impact on the brain”
Photo Credit: Courtesy of Concordia University

Individuals with coronary artery disease (CAD) — a constricting or blocking of blood vessels feeding the heart — face increased risks of strokes, cognitive impairment and dementia. However, the link between CAD and cognitive function is not fully understood. 

A new study led by Concordia researchers looks at how the disease affects the brain’s white matter, the network of nerve fibers that connects different regions of the brains and is critical to transmitting information efficiently. 

The study, published in the Journal of Neuroscience, applied a novel multivariate approach using 12 separate metrics. The researchers compared test results and MRI scans of 43 patients with CAD to those of 36 healthy individuals. All participants were over the age of 50. 

Microplastics pose a human health risk in more ways than one

Bio-beads collected near Truro.
Photo Credit Beach Guardian

A new study shows that microplastics in the natural environment are colonized by pathogenic and antimicrobial resistant bacteria. The study team calls for urgent action for waste management and strongly recommends wearing gloves when taking part in beach cleans. 

Microplastics are plastic particles less than 5mm in size and are extremely widespread pollutants. It is estimated that over 125 trillion particles have accumulated in the ocean (surface to seabed) and they have also been detected in soils, rivers, lakes, animals and the human body. 

An emerging concern associated with microplastics is the microbial communities that rapidly make their home on the particle surface, forming complex biofilms known as the “Plastisphere”. These communities may often include pathogenic (disease-causing) or antimicrobial resistant (AMR) bacteria. 

The seamounts of Cape Verde: a biodiversity hotspot and a priority for marine conservation in the central-eastern Atlantic

Image Credit: Projecte Luso/iMirabilis2/iAtlantic

An international team led by Covadonga Orejas, a researcher at the Gijón Oceanographic Centre of the Spanish Institute of Oceanography (IEO-CSIC); Veerle Huvenne, a researcher at the UK National Oceanography Centre (NOC); and Jacob González-Solís, professor at the Faculty of Biology and the Biodiversity Research Institute (IRBio) of the University of Barcelona, has published the first comprehensive study on the seamounts of the Cape Verde archipelago, their biodiversity, ecological functionality and socio-economic relevance in the journal Progress in Oceanography.

These volcanic formations — at least 14 large mountains and numerous smaller elevations — act as veritable oases of life in the deep ocean, concentrating nutrients and modifying the circulation of underwater currents. This supports exceptional biodiversity, ranging from microorganisms to communities of deep-sea corals and sponges, as well as sharks, turtles, seabirds and cetaceans. Their position between the temperate waters of the North Atlantic and the tropical waters of the South, further enhances their productivity and ecological connectivity. 

Ecological winners: Why some species dominate the planet

A new study sheds light on why some species seem to thrive nearly everywhere, while others are rare and have very limited ranges. Pictured is the boojum tree (Fouquieria columnaris), native only to a few desert regions in Mexico's Gulf of California. 
Photo Credit: Daniel Stolte

Few ideas in science have been tested and confirmed as thoroughly as evolution by natural selection. 160 years ago, Charles Darwin proposed the theory of evolution by natural selection after observing organisms that had developed highly specialized traits to better survive or reproduce in their environments. Whether the same process can explain global patterns of biodiversity, however – why most species are restricted to certain environments while a few outliers seem to be found everywhere – remains largely uncertain.

"We still are not exactly sure why most species are confined to narrow ranges, while only a few thrive nearly everywhere," said Brian Enquist, professor in the University of Arizona Department of Ecology and Evolutionary Biology and senior author of a new study providing the strongest global evidence yet that abundant plant species became so dispersed over time because of their ability to tolerate diverse climates.

Looping long-necked dinosaur site reveals its secrets

An aerial view of the loop section of the West Gold Hill Dinosaur Tracksite in Colorado.
Photo Credit: Dr. Paul Murphey

An analysis of a unique looping trail of ancient footprints in the United States reveals the dinosaur which made it may have been limping. 

The site near Ouray in Colorado is one of the most continuous and tightly turning sauropod trackways ever documented. 

Dr. Anthony Romilio from The University of Queensland’s Dinosaur Lab analyzed more than 130 footprints along the 95.5-metre track made 150 million years ago. 

“This was left in the Late Jurassic when long-necked dinosaurs such as Diplodocus and Camarasaurus roamed North America,” Dr Romilio said. 

Why the "gut brain" plays a central role for allergies

This tissue section, taken from the intestine of a mouse unable to produce the neuropeptide VIP, clearly shows the striking frequency with which certain cell types occur on the intestine's surface. These include villous cells (red), mucus-producing goblet cells (yellow), Paneth cells (pink) and stem cells (green).
Image Credit: © Charité | Luisa Barleben

The intestinal nervous system, often referred to as the "gut brain", is essential in controlling digestion and maintaining the intestinal barrier. This protective layer, made up of the intestinal mucosa, immune cells and the microbiome, shields the body from the contents of the gut. Its effectiveness depends on the delicate balance among these components. If this balance is disrupted, inflammation, allergies, or chronic intestinal diseases can arise. The intestinal mucosa serves as the body’s primary defense against pathogens. While previous studies have shown that the intestinal nervous system is involved in immune responses in addition to digestion, its role in the development of intestinal epithelial cells has remained largely unclear until now. 

Ichthyology: In-Depth Description

Image Credit: Scientific Frontline / AI generated

Ichthyology is the specialized branch of zoology devoted to the scientific study of fish, encompassing all three major groups: jawless fish (Agnatha), cartilaginous fish (Chondrichthyes), and bony fish (Osteichthyes). This discipline investigates the biology, morphology, taxonomy, evolution, and behavioral patterns of the most diverse group of vertebrates on Earth, ranging from microscopic species to massive biological entities like whale sharks.

Stroke scientists gather more evidence for presence of ‘gut-brain axis’

Image Credit: Scientific Frontline / stock image

Research on mice by scientists at The University of Manchester has shed new light on why the guts’ immune system changes after a stroke and how it might contribute to gastro-intestinal problems. 

Published in Brain, Behavior and Immunity, the study adds to the emerging idea of the “gut-brain axis” – in which scientists suggest allows communication between the two organs in both health and disease. 

The study casts more light on the biology of stroke, a life-threatening medical emergency that disrupts blood flow to parts of the brain often causing long-term effects to mobility and cognition. 

Stroke patients are also at risk of secondary bacterial infections and often exhibit gastrointestinal symptoms including difficulty swallowing and constipation. 

Genetics: In-Depth Description

Image Credit: Scientific Frontline / stock image

Genetics is the branch of biology concerned with the study of genes, genetic variation, and heredity in organisms. It seeks to understand the molecular mechanisms by which traits are passed from parents to offspring, how the genetic code directs biological functions, and how variations in this code drive evolution and disease. At its core, genetics is the study of biological information: how it is stored, copied, translated, and mutated.

Consciousness as the foundation – new theory of the nature of reality

Maria Strømme, Professor of Materials Science.
Inset Photo Credit: Courtesy of Uppsala University

Consciousness is fundamental; only thereafter do time, space and matter arise. This is the starting point for a new theoretical model of the nature of reality, presented by Maria Strømme, Professor of Materials Science at Uppsala University, in the scientific journal AIP Advances. The article has been selected as the best paper of the issue and featured on the cover. 

Strømme, who normally conducts research in nanotechnology, here takes a major leap from the smallest scales to the very largest – and proposes an entirely new theory of the origin of the universe. The article presents a framework in which consciousness is not viewed as a byproduct of brain activity, but as a fundamental field underlying everything we experience – matter, space, time, and life itself.